Glimeto-M2 Tablets

Composition

• Metformin Hydrochloride (Prolonged Release) – 500 mg
• Glimepiride – 2 mg

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Mechanism of Action

Metformin Hydrochloride (Prolonged Release) reduces hepatic glucose production, enhances insulin sensitivity, and increases peripheral glucose uptake. Its prolonged-release formulation ensures gradual drug release, offering sustained blood glucose control with better gastrointestinal tolerability.

Glimepiride stimulates insulin secretion from pancreatic beta cells, helping lower blood glucose levels effectively and improving overall glycemic balance.

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Key Benefits

• Dual-action mechanism for effective glucose control
• Helps reduce fasting and postprandial blood sugar levels
• Supports HbA1c reduction
• Sustained release for prolonged therapeutic effect
• Improves insulin sensitivity
• Suitable for once-daily dosing as prescribed

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Indications

• Type 2 Diabetes Mellitus
• Patients inadequately controlled on single-drug therapy
• Combination therapy for improved glycemic management

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Dosage & Administration

• To be taken as directed by the physician
• Usually taken with meals
• Tablets should be swallowed whole and not crushed or chewed

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Precautions

• Increased risk of hypoglycemia due to sulfonylurea component
• Use cautiously in renal or hepatic impairment
• Regular blood glucose monitoring is recommended
• Avoid excessive alcohol intake

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Contraindications

• Type 1 Diabetes Mellitus
• Diabetic ketoacidosis
• Severe renal or hepatic impairment
• Known hypersensitivity to any component

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Storage

• Store in a cool and dry place below 25°C
• Protect from light and moisture
• Keep out of reach of children

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Packaging

• 10 x 15 Tablets